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Thursday, May 14, 2020 | History

3 edition of Epilepsy and the oral manifestations of phenytoin therapy found in the catalog.

Epilepsy and the oral manifestations of phenytoin therapy

by Thomas Michael Hassell

  • 277 Want to read
  • 27 Currently reading

Published by Karger in Basel, London .
Written in English

    Subjects:
  • Epilepsy -- Chemotherapy.,
  • Phenytoin -- Physiological effect.

  • Edition Notes

    Includes bibliographies and index.

    StatementThomas Michael Hassell.
    SeriesMonographs in oral science -- v.9
    Classifications
    LC ClassificationsRC374.P/
    The Physical Object
    Paginationxiv,205p. :
    Number of Pages205
    ID Numbers
    Open LibraryOL21867061M
    ISBN 10380551008X

    Oral benzodiazepines are not frequently used alone in primary treatment of epilepsy, although sometimes a useful adjunct in both focal and generalized seizures. Principles for the Management of epilepsy. Attempt to classify, localize and investigate underlying etiology. Not every seizure is an indication for anticonvulsant therapy.   Pathophysiology and management of epilepsy 1. PATHOPHYSIOLOGY & MANAGEMENT OF EPILEPSY T. SOUJANYA PHARM.D 2. DEFINITION: Epilepsy is a common neurological condition characterized by recurrent seizures (that usually occur unpredictably), loss of consciousness with or without body movements.

    Epilepsy has direct negative effects on sufferers' general dental condition and oral health, both of which are further af-fected by inadequate oral hygiene; poor oral hygiene itself is often also. -"Phenytoin (Dilantin) should always be taken with food or milk." Rationale: This medication should be taken with food or milk. Patients taking phenytoin (Dilantin) therapy usually have a decrease in appetite, experience drowsiness after taking the medication, and experience pinkish red or reddish brown urine, which is harmless.

    PHENYTOIN DOSE ADJUSTMENT 2 1a) lL C _0 *0 0 E I-I c _o0 cc Ca)0 c8 C._ a E C5 0. 0 0 0 0 0 * 0 0 )L..O*-O -. *0 I I I 0 10 20 30 Serumphenytoin concentration(pg/mi) Fig. 1 Relationship between the frequency of grand mal attacks and the serum phenytoin concentration. Manypatientswith incompletecontrol of epilepsy had serum phenytoin concentrations belowthelowerlimit ofthe Cited by: Clinical guideline for the use of phenytoin in epilepsy Page 3 of 12 3. Phenytoin dosing Use the red supplementary drug chart for an IV prescription. Sample prescription – example 70kg patient: IV loading dose For phenytoin-naïve patients, loading doses can be calculated as follows: Weight (kg) Dose (mg/mL) mg in mLFile Size: KB.


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Epilepsy and the oral manifestations of phenytoin therapy by Thomas Michael Hassell Download PDF EPUB FB2

Epilepsy and the oral manifestations of phenytoin therapy. Basel ; New York: Karger, (OCoLC) Online version: Hassell, Thomas Michael. Epilepsy and the oral manifestations of phenytoin therapy. Basel ; New York: Karger, (OCoLC) Material Type: Internet resource: Document Type: Book, Internet Resource: All Authors.

Monogr Oral Sci. ; Epilepsy and the oral manifestations of phenytoin therapy. Hassell TM. PMID: [PubMed - indexed for MEDLINE]Cited by: Epilepsy and the oral manifestations of phenytoin therapy. Basel ; New York: Karger, (OCoLC) Material Type: Document, Internet resource: Document Type: Internet Resource, Computer File: All Authors / Contributors: Thomas Michael Hassell.

Epilepsy and the Oral Manifestations of Phenytoin Therapy (Monographs in Oral Science, Vol. 9) [T.M. Hassel, A. Lussi, M.C.D.N.J.M. Huysmans, H.-P. Weber] on Amazon Cited by: Epilepsy and the oral manifestations of phenytoin therapy. From inside the book. What people are saying - Write a review.

We haven't found any reviews in the usual places. 5,5-diphenylhydantoin action of PHT activity administration animals anticonvulsant anticonvulsant drugs anticonvulsant therapy Antiepileptic drugs Archs Neurol brain. Open Library is an open, editable library catalog, building towards a web page for every book ever published.

Epilepsy and the oral manifestations of phenytoin therapy by Thomas Michael Hassell,Karger edition, in EnglishCited by: Because of its relative lack of sedation and ease of loading by a parenteral route, the mainstay of acute seizure treatment in the United States remains phenytoin, although it is not clearly efficacious in all circumstances (e.g., hypoglycemia or alcohol withdrawal).

The recent availability of fosphenytoin provides more flexibility, mainly by allowing intramuscular. Phenytoin (FEN-ih-toe-in) is the generic name (non–brand name) of a widely used seizure medicine.

Common brand names for this type of medicine include Dilantin, Phenytek, and Epanutin (in the UK), but it is also sold using the name phenytoin or phenytoin sodium. Using generic medicines rather than brand-name ones is often suggested as a way. A seizure is the manifestation of an abnormal, hypersynchronous discharge of a population of cortical neurons.

This discharge may produce subjective symptoms or objective signs, in which case it is a clinical seizure, or it may be apparent only on an electroencephalogram (EEG), in which case it is an electrographic (or subclinical) seizure.

Clinical seizures are usually classified according to. shown efficacy in the early treatment of status epilepticus. In hospitalized patients with status epilepticus, intravenous lorazepam is the drug of choice for initial emergency therapy. In a clinical trial of adults with in-hospital status epilepticus, intravenous lorazepam was superior to intravenous phenytoinFile Size: KB.

In one report, nerve conduction studies were abnormal in 15 of 21 children with epilepsy receiving long-term phenytoin therapy. The most frequent The most frequent Antiseizure drugs: Mechanism of action, pharmacology, and adverse effects View in Chinese.

Generic name: Phenytoin Available as: Epanutin, Phenytoin, Phenytoin Sodium Flynn Anti-epileptic drugs (AEDs) are the main form of treatment for people with epilepsy. And up to 70% (7 in 10) people with epilepsy could have their seizures completely controlled with AEDs.

ABSTRACT. Objective: Long-term use of phenytoin (PHT) causes gingival hyperplasia; however, little is known about the oral side effects of other antiepileptic drugs (AEDs). Through a systematic review of the literature, we explored the effects. Methods:A total of 25 patients aged between 18 and 50 years, clinically diagnosed with epilepsy prior to the start of phenytoin therapy were included based on selection criteria and written informed consents were obtained.

Assessment of serum folic acid levels and gingival enlargement was done prior to the start of and after 6 months of. Phenytoin Sodium Pharmacokinetics Absorption Bioavailability.

Studies using Dilantin have shown that phenytoin and its sodium salt are usually completely absorbed from the GI tract. Bioavailability may vary enough among oral phenytoin sodium preparations of different manufacturers to result in toxic serum concentrations or a loss of seizure control; this should be considered before.

For this reason, serum phenytoin concentrations may increase modestly when IV phenytoin is substituted for oral phenytoin sodium therapy. The rate of administration for IV phenytoin should be no greater than 50 mg per minute in adults and mg/kg/min (or 50 mg per.

Phenytoin is an anticonvulsant medication that is used to control seizures. Phenytoin does not treat all types of seizures, and your doctor will determine if it is the right medicine for you.

Phenytoin may also be used for purposes not listed in this medication guide. What are the possible side effects of phenytoin. Long-term phenytoin therapy is known to cause disturbance in calcium and bone homeostasis. Dental tissues being calcified tissues can also be affected by this derangement of mineral metabolism, especially during developmental phases.

This report describes a case of an epileptic child who presented with short roots, enlarged pulp chambers, blunt apices and delayed eruption of Cited by: 1. Whenever occurs, this adverse effect of phenytoin, lasts throughout the period of therapy and continues further with a severe reduction in the quality of life of the affected individual.

Epilepsy is a common neurological disorder with recurrent seizures due to a chronic underlying process. International League Against Epilepsy (ILAE) The ILAE Classifications of Seizures and the Epilepsies have been used since Although imperfect, they have provided invaluable means of communication Efforts continue to refine and upgrade the current classifications Based on review of video recorded seizures of clinical and electroencephalographic events.

Epilepsy is initially treated with antiseizure drug monotherapy. Almost half of patients will become seizure-free with their first antiseizure drug trial [ 22,23 ].

In choosing an initial therapy, clinicians must weigh relative efficacy and potential for adverse effects of each .J.R. Babcock, Incidence of gingival hyperplasia associated with Dilantin therapy in a hospital population JADA 6 () T.M.

Hassell, Epilepsy and the oral manifestations of phenytoin therapy () Kruger Publishers Basel, Switzerland Cited by: Epilepsy is a brain disorder that causes people to have recurring seizures. The seizures happen when clusters of nerve cells, or neurons, in the brain send out the wrong signals.

People may have strange sensations and emotions or behave strangely. They may have violent muscle spasms or lose consciousness. Epilepsy has many possible causes.